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16, 2025 from Rubino, D., Abrahamsson, N., Davies, M., et al (2021)

Delay gastric emptying: Slows gastric emptying, which helps in reduce postprandial glucose excursions (the change in glucose concentration from before to after a meal) and promote satiety

These types of medications were initially developed for treatment of diabetes by affecting the bodys glucagon-like peptide-1 (GLP-1) receptors

However, concerns have been raised regarding their safety, particularly the risk of gastrointestinal (GI) adverse events

Prior authorization requirements and step therapy protocols often complicate the approval process even when theoretical coverage exists