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Its broad therapeutic scope creates many overlaps with other main groups and internally across N01N07 (Table 2 and S1)

In the context of T2D, the ability of GIP to stimulate insulin secretion and to ameliorate glycaemia is impaired [35]

In another study in volume-loaded participants, GLP-1 induced natriuresis together with the ANG II level decrease, independent of renal hemodynamics (renal plasma flow, GFR unchanged) and renin concentrations 37