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Furthermore, at 10 M concentration, BAPN would exclusively inhibit lysyl oxidases (IC 50 (LOX) = 5 M), whereas Semicarbazide-sensitive amine oxidase (SSAO) would not be affected at this concentration (IC 50 = 4 mM) 45
On admission, her vital signs were stable: Glasgow Coma Scale 15, body temperature 36.4C, heart rate 70 beats per minute, blood pressure 139/76 mmHg, respiratory rate 17 breaths per minute, and oxygen saturation 99% on room air
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Days 5-14: Gradual Improvement Receptor desensitization begins
HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques
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