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Additionally, GLP-1RAs tend to stimulate the AMP-activated protein kinase pathway, which in turn will modulate stress and shift the intracellular macrophages to the M2 subtype while decreasing the M1 subtype in the bloodstream[30-32]

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Int J Mol Sci 22:9936

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The results indicated a significant increase in resting metabolic rate (RMR), with a 7.2% to 8.4% rise from baseline within 4 h post-intake

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