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As one of the main endogenous antioxidants in the human body, UA contributes up to 60% of the plasma antioxidant capacity, which can protect cells from oxidative stress (Sautin and Johnson, 2008)

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The nicotine concentration of 100% CSE and 100% HTP used in the present study are 198 g/mL and 34.8 g/mL, respectively (Fig