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In both THP1 cells and primary human peripheral blood macrophages, the half-life of NLRP3 was slightly longer (~ 56 h in an unchallenged condition) than in U937 cells (~ 4 h in an unchallenged condition) [6]

It also takes a very narrow view of coststhere would also be economic costs to her premature death, which we deal with in the following section, as well as the very substantial personal cost to her and loved ones of her lost years of life and the suffering that comes with lung cancer

That feature fits Gorillas larger philosophy: budgeting should help production teams make decisions earlier, not merely record costs later

Of note, the ageing lung shows morphological changes that resemble emphysema in COPD, including alveolar enlargement and a reduction in elastic recoil, contributing to lung function decline [42]