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Discussion Since the COVID-19 pandemic, the prevalence of substance use, including tobacco products, marijuana, opioids, and alcohol, has been increasing, especially among men of reproductive age 28,29

The concern would be that, for nonsmokers and teens, e-cigs become a gateway to nicotine addiction. In addition, the long-term effects of substances found in vape liquids, like propylene glycol, are still unknown, so until we have more definitive data, caution is the watchword