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While estimates often range from $117,000 to $466,000, our experience shows that a comprehensive application can easily exceed $1 million, depending on the complexity of your product
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and (3) annual direct costs for health care ($4,440.7 million) are 31 times higher, and annual direct costs for enforcement ($5,407.7 million) are 36 times higher than annual costs for prevention and research ($147.6 million)." Thomas, Gerald and Davis, Christopher G., Comparing the Perceived Seriousness and Actual Costs of Substance Abuse in Canada: Analysis drawn from the 2004 Canadian Addiction Survey," Canadian Centre on Substance Abuse (Ottawa, ON: Canadian Centre on Substance Abuse, March 2007), pp
Methods/Design Design This study will examine the effects of plain versus branded cigarette packaging on smoking behavior and experiences of smoking among a sample of adult daily smokers
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