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That's important because tobacco use remains the leading cause of preventable deaths in the U.S.and nearly 95% of adult smokers say they started using tobacco before 21

It is, therefore, conceivable that the carcinogens taken within ETS can also cause OSCC in NSND, for which the mechanisms of formation with different lifestyle factors are still largely unknown, and furthermore, the carcinogens can increase the risk of OSCC in active smokers 15,28

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