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Alternatively, nic salts and high-VG e-liquids will have a lessened throat hit, more comparable to disposable vapes

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The agonists (activators) of these three types of receptors (of which the best known are THC for the cannabinoid receptors, nicotine for the nicotinic receptors and morphine for the opioid receptors) are hugely important in terms of the psychoactive and physiological effects they can exert