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Its characterized by the presence of at least three of these symptoms and develops within seven days of reduced marijuana use: 5 Irritability, anger, or aggression Nervousness or anxiety Sleep disruptions Changes in appetite or weight Restlessness Depressed mood Somatic symptoms: headache, nausea, sweating Who Is At Risk for Marijuana Abuse

(See Concomitant Use with Opiates under Cautions and also see Specific Drugs and Laboratory Tests under Interactions.) Psychiatric Indications Do not use in patients with depressive neuroses or psychotic reactions in which anxiety is not prominent