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At very high PM2.5 levels, such as those seen during severe pollution episodes, long term exposure can be comparable to smoking multiple cigarettes per day, depending on duration and concentration

E-cigarettes are sold to over-18s, e-liquid is capped at 20mg/ml of nicotine with refill tanks limited to 2ml, and there is no flavour ban

All case definitions for diseases and exposure (ST use) used in the retrieved articles were checked for accuracy and consistency and all analyses undertaken in these studies were assessed to see if they controlled for key confounders (mainly smoking and alcohol)

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