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Nicotine addiction is no different and its properties include: Psychoactive effects Compulsive use Quick relapse Drug-reinforced behavior Tolerance Physical dependence Nicotine can act as both as a stimulant and a sedative, depending on the quantity you ingest

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Since the proposed payment methodology for the new add-on code for Opvee (GOTP1), the weekly bundled payment for weekly Brixadi (GOTP2), and the update to the monthly bundled payment for injectable buprenorphine (HCPCS code G2069) is based on comparable and existing drugs billed under the Medicare OTP benefit, and assuming an OTP may provide these new drugs to a Medicare beneficiary in lieu of the comparable ( and existing drugs under the Medicare OTP benefit ( e.g., Opvee instead of Narcan or Kloxxado, or the weekly or monthly formulation of Brixadi instead of Sublocade), then CMS estimates the financial impacts of these new drugs would be negligible

We believe that these changes are appropriate as they further account for patient heterogeneity in the more clinically diverse patient cohort