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Aside from the ability to hold more e-liquid, vape tanks are often made of glass instead of plastic

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A decrease in drug metabolism is shown in vapes containing flavouring agents such as benzaldehyde and cinnamaldehyde that are potent inhibitors of the CYP2A6 enzyme, which is primarily responsible for the metabolism of nicotine, leading to an increase in plasma concentration levels of nicotine (Winters et al