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ENDS users showed acute worsening of BP, HR and [heart rate variability], as well as vasoconstriction, impaired exercise tolerance and increased airflow obstruction after using ENDS compared with control participants, Tattersall and colleagues wrote

A Nairametrics research as at 2016 suggests that about 21 billion sticks of cigarettes were produced in the country

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It claims 72 percent of IQOS users quit smoking, and that the device has taken over one-tenth of Japans tobacco market

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