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Bupropion SR, nicotine gum, lozenges, inhalers, nasal sprays and patches, and varenicline were approved by the FDA to assist cigarette smokers with tobacco cessation

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There had been a trend for manufacturing cigarettes with lower nicotine yield in recent decades but at the same time there is a reported tendency for the smokers of such low-nicotine yield cigarettes to smoke more intensely and to inhale the smoke more deeply than the smoker of plain cigarettes [15]