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This radical move made designer fashion accessible beyond the elite, forever changing the industry and establishing the framework that luxury houses still follow today

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Int J Environ Sci Technol 14:13711382 Cragg GM, Pezzuto JM (2016) Natural products as a vital source for the discovery of cancer chemotherapeutic and chemopreventive agents

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According to studies by the National Cancer Institute, regular exposure to tobacco smokewhether from cigarettes or cigarscan lead to a higher risk of certain cancers, especially those affecting areas it comes in direct contact with, like the mouth and throat