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While intellectually accepting the prevailing codes, Orwell's inner self maintained an emotional rebellion, recognizing the gap between expected feelings (gratitude to cruel benefactors) and actual feelings (hatred)

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Integrative analyses showed associations between microbial composition and host gene expression, such as CD74 positively correlated with Lactobacillus and PPP1R3C negatively with Bacteroidota, suggesting that smoking-induced microbial shifted might interact with host transcriptional programs to promote OSCC progression [59]