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Knowing that combustible tobacco use is the leading cause of preventable death, oral nicotine product use may be a relatively lower-harm alternative if people who smoke stop smoking all together

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In the oldest age groups, people aged 75 and older had a daily smoking rate of 3.3% (95% CI: 2.1-4.9), for people aged 65 to 74 it was 6.0% (95% CI: 4.7-7.7) (Appendix 1- Figure A3)

The slides were then rinsed with PBS buffer and mounted with a 1:1 (v/v) PBS/glycerol solution before being stored at 4 C overnight