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It binds to acetylcholine receptors located on dopaminergic neurons and chromaffin cells of the brain

Leaving aside the 15-24 year old group (high quit rates may reflect frequent cycling between smoking and being quit in this age group), there was a seven fold variation in quit rates from 28% among 25-34 years to less than 4% among over 75 year olds

If you have ready rubbed (and we'd really recommend this as a starting point) you're more or less all set

One study that compared nicotine doses between heavy smokers and e-cigarette users found that vaping devices deliver nicotine at slightly lower levels than cigarettes

The problem with that assertion is that up to half the nicotine used in these products may still be derived from tobacco plants