The fact that the additives lead to more TPM is, itself, an important indicator of increased toxicity because the TPM in cigarette smoke leads to substantial increases in risk of cardiovascular disease, with a steep and highly nonlinear dose-response at low levels of exposure [123][126]
Careful evaluation of these alternatives can help individuals choose the most suitable smoke protection method based on their specific needs and circumstances
This exercise yielded 194 statistically significant changes (compared to the 26 reported in PM's published paper, Text S1,Table S-3), suggesting that a better powered study would have detected a much broader range of biological effects associated with the additives than identified in PM's published paper [18], suggesting that it substantially underestimates the toxic potential of cigarette smoke and additives
All the examples youve given us are of dead people? she said
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