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Among the oral antidiabetic medications currently available, pioglitazone, dapagliflozin, and canagliflozin are known, like other drugs, to be metabolized by CYP450 enzymes, which can be affected by compounds found in cigarette smoke

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Made: 1999 This image is released under a CC BY-NC-SA 4.0 Licence License this image for commercial use at Science and Society Picture Library License Packet of 20 Gauloises Legeres filter cigarettes, king size Science Museum Group The Board of Trustees of the Science Museum Packet of 20 Gauloises Legeres filter cigarettes, king size, marked for exportation, made in France by Seita, 1999

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Females with HS should discuss this with their dermatologist or ob/gyn