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Such methodologies should allow for a direct comparison of (i) toxicant emissions, (ii) a broad range of toxicity endpoints and (iii) reductions in toxicant exposure, to ensure that a given cMRTP is equivalent to, or better than, the reference MRTP

If you don't smoke, don't smoke

In The Next Generation -era of Star Trek, there were limited scenes involving smoking

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Researchers who combined data from more than 320,000 adults found that people who smoked 25 cigarettes daily had about a 50% higher risk of heart failure and a roughly 60% greater risk of death from any cause, compared with people who never smoked