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Based on our research, once there is lymph node metastasis, lung cancers with a GGO component have an equally bad prognosis to their solid counterparts. This and other work raise concerns about limiting LDCT screening for lung cancer to older, long-term smokers, as is currently done in many Western countries based on the results of the National Lung Screening Trial and the NELSON trial

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A review from 2022 indicated smoking increases the risk of fibrosis progression across many liver diseases with varied causes, such as primary biliary cholangitis and chronic hepatitis infection