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typhimurium strains TA 98, TA 100, and TA 102.[] Occupational exposure to bidi tobacco was found to result in direct urinary mutagenicity in strain TA 98 and upon treatment with B glucuronidase among bidi rollers, while the samples from tobacco processors exhibited direct mutagenicity in strains TA98, TA100, and TA102.[] Toxic effects on cells: Treatment of Syrian golden hamster tracheal epithelial cell line (HTE) with a non-toxic dose of an aqueous extract of bidi tobacco induced cellular hypertrophy, widening of intercellular spaces, and stimulated ornithine decarboxylase activity and the rate of DNA synthesis

Common symptoms of lung cancer include a long-lasting and worsening cough, chest pain, shortness of breath, fatigue, wheezing, and chronic and recurring infections, such as pneumonia and bronchitis

10.1093/ntr/ntaa058 98

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