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NIX-mediated mitophagy expression reduces the mitochondrial network and increases the conversion of glucose to lactate through glycolysis, providing sufficient energy for cancer cells

Health and Social Care Information Centre, 2015

The interventions are itemised in a Population-Intervention-Comparison-Outcome (PICO) structured table (Table 1)

To express mitoQC in N2a cells, the GFP cDNA was excised from a pAAVhSynEGFP plasmid (Addgene plasmid # 50465) using the KpnI and EcoRI restriction sites

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