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Acknowledgements This work was funded by the National Nature Science Foundation of China for Young Scholars (No

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Although not infectious, the fever in these decades had reached the equivalent of epidemic proportions and must have hampered workplace productivity, considering the scope of the symptoms DuPont describes from its survey of complaints registered by workers struck by the illness: tightness of chest, malaise, shortness of breath, headache, cough, chills, temperatures between 100 and 104 F, and sore throat

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