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An expert independent evidence review published today by Public Health England (PHE) concludes that e-cigarettes are significantly less harmful to health than tobacco and have the potential to help smokers quit smoking

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Nicotine stimulates the brains reward centres, causing a burst of energy and pleasure

Scientists have identified a biochemical pathway in the brain that mediates the nicotine-triggered mechanism by which cigarette smoking suppresses appetite

Most people recover without long-term effects, though repeated stings over lifetime can increase sensitivity