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Under that rule, all electronic nicotine delivery systems (ENDS) needed FDA authorization to be legally marketed in the United States

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"Our data shows that e-cigarettes have a signature of harm in the lung that is both similar to what we see in cigarette smokers and unique in other ways," said Mehmet Kesimer, from the UNC School of Medicine

These drugs interact with serotonin receptors in the brain, affecting mood and sensory processing