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Table 1 Chemical combustion products from cigarettes, their health hazards, and effects specific to electronic cigarettes A complex mixture of combustion products, cigarette smoke can include more than 7,000 different chemicals and up to 110 17 free radicals, including both reactive oxygen species (ROS) and reactive nitrogen species (,)

who had never smoked traditional cigarettes and who were not susceptible to smoking at the time

IQOS (heated tobacco product) is also less toxic than cigarettes, with reductions of 85% and 96% in the concentration of these toxic compounds, but these reductions nevertheless remain lower than those observed with e-cigarettes, in line with previous studies

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