It has the same addictive nicotine of cigarettes, and thousands of toxic chemicals, many known to be carcinogenic
Most users of chewing tobacco in the USA are men, though some American Indian and Alaskan Native communities typically have a relatively high prevalence of using these products
Pediatrics 2010;125(5):8969 [cited 2014 Oct 31]
There is a large body of toxicological, experimental, and epidemiological data, collected since the 1950s, that has established that tobacco use is the largest preventable cause of morbidity and mortality in the world, producing more than 5 million deaths a year
Increased Heart Rate: Smoking can stimulate the heart, leading to increased heart rate and blood pressure, which may result in acute cardiovascular stress