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Indeed, tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis, can exacerbate or trigger certain mental health conditions, especially with frequent or high-dose use

The laxative side effect of nicotine is not meant to be the main purpose, and due to the addictive nature of nicotine, it is not recommended that you use nicotine as a laxative

There could be lots of reasons why the episode ended up so light on sketches and characters for Chappelle, but the most likely culprit was the length of the monologue

News release: Cristiano Ronaldo: Coca Cola gesture followed by $4bn drop in company's market value

This inhibition disrupts normal brain function, leading to sedation and muscle relaxation