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Since 2024, tobacco monopoly authorities at various levels, working together with public security agencies and customs anti-smuggling departments, have uncovered multiple cases involving the smuggling of e-cigarettes, delivering effective blows to illicit trade networks and continuously improving the order of e-cigarette import and export activities

One plausible mechanism linking smoking to OA is oxidative stress, which results from the generation of reactive oxygen species by cigarette smoking, it can directly injure chondrocytes and suppress the synthesis of crucial extracellular-matrix components, ultimately driving cartilage breakdown 27

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