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The lack of combustion and the reduced formation of harmful chemicals should be substantiated on a product-by-product basis

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We also found that lung endothelial damage after switching from cigarettes to IQOS did not match the efficiency by which cessation of cigarette exposure reduced it

Meliker JR, Slotnick MJ, AvRuskin GA, Schottenfeld D, Jacquez GM, Wilson ML et al (2010) Lifetime exposure to arsenic in drinking water and bladder cancer: a population-based casecontrol study in Michigan, USA

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