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Out of the 50 studies analyzed, only 2 were randomized controlled trials

Short term Looks grey and dull Long term Delayed wound healing Increased infections Causes cellulite Ages more quickly Three times more likely to get wrinkles Bones disease The chemicals and nicotine in smoking affect the metabolism of hormones, vitamin D levels, calcium absorption, blood circulation and thus significantly affects bone formation and healing

Jun, [Google Scholar] 21.Center for Tobacco Products FUDoHaHS

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In addition, this study revealed that as smoking intensity and cumulative dose of smoking increased in females, serum uric acid levels and frequencies of hyperuricemia and gout also increased