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Comprised of Virginias, Burleys, and a proprietary tobacco that was specially created by Milan's master blender David Meyer to take this aromatic blend to new heights of pipe smoking enjoyment

Whole cigarettes (3 cigarettes from 3 different packages of the same variety) were extracted and analyzed in triplicate for the major commercial sensory cooling agents (menthol, WS-3, WS-23, WS-12, Frescolat MGA, Frescolat ML, Frescolat X-cool) by gas chromatography - mass spectrometry following published protocols (Supplementary file) 3

Each candidate solution in the population represents a binary feature selection vector, where selected features contribute to classification decisions

Confounding Smoking is increasingly concentrated in socially disadvantaged populations in many settings (eg, as per this European study 24 ), and these populations usually have higher rates of other risk factors for non-communicable diseases

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