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Additionally, there is a need for more mechanistic studies in humans and standardized epigenetic biomarkers to improve understanding of the persistence and functional consequences of tobacco-induced epigenetic changes

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El objetivo de este estudio fue analizar si determinados polimorfismos genticos en los loci que forman parte de la cascada de reparacin del ADN se asocian con el cncer de pulmn de clula no pequea, y tambin si es posible que modifiquen la asociacin entre la exposicin al radn en el hogar y el cncer de pulmn tanto en fumadores como en no fumadores