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How chewing tobacco accelerates cancer Chewing tobacco contains multiple carcinogens, including tobacco-specific nitrosamines (TSNAs), which are among the most potent cancer-causing substances found in tobacco, according to cancer.gov

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Overall, not only are flavors appealing and palatable, they also counteract the unpleasant sensory effects that are inherent to nicotine, such as a bitter taste and irritation in your airways, said Adam Leventhal, director of the Institute for Addiction Science at the University of Southern California