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In these contexts, the brand carries symbolic value beyond the act of smoking itself

At the preclinical level, while some studies have modeled CWS using spontaneous withdrawal (abrupt cessation of drug treatment), the far more prevalent model is withdrawal precipitated by CB1 antagonist/inverse agonist administration, which immediately blocks the effects of the chronically administered cannabinoid drug [37]

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Al-Marzooq F, Al Kawas S, Rahman B, Shearston JA, Saad H, Benzina D, et al

Approximate burn time of 50 hours