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[26] on the other hand, only examined current e-cigarette use, without accounting for prior smoking history: had there been a significant association between e-cigarette use and onset of respiratory symptoms, it could be due to prior cigarette smoking, in which case adjusting for pack-years would be necessary (though not necessarily sufficient) to account for this [14]

Notably, High-income Asia Pacific is the only region globally where the rise in disease burden is mainly driven by population aging (DALYs: 96.52%, Deaths: 410.93%), significantly outweighing the influence of population growth (DALYs: 93.71%, Deaths: 260.97%)