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The extreme heat breaks down the active amphetamine compounds, often destroying the very chemicals the user is trying to ingest

A potential concern is that our use of a saline/ETOH solvent for extract preparation may have influenced our findings due to the well-established abuse liability of ETOH and its potential effects on MAO activity (Truman et al., 2019), as well as the ability of ETOH to interact with nicotine on certain measures of abuse liability (e.g., Schaefer and Michael, 1992

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