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There are studies that have shown that life expectancy is shortened by 10 years as a firefighter and that the most frequent causes of death are typically cardiovascular disease

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Rostami-Hodjegan A, Amin AM, Spencer EP, Lennard MS, Tucker GT, Flanagan RJ (2004) Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patients