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While nicotine isn't known for major long-term harm, it can be particularly risky for those with heart or nervous system conditions

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The fact that the one approved product, IQOS by Philip Morris International, purportedly required billions of dollars for regulatory compliance on the part of the manufacturer and experienced two years of regulatory delay until approval does not bode well for any maker of e-cigarettes, apart from the largest tobacco manufacturers

doi:10.1164/rccm.201909-1809LE

Can I use nicotine pouches where vaping is banned