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The following serious adverse reactions with the use of COCs are discussed elsewhere in the labeling: Adverse reactions commonly reported by COC users are: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to the rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice

Janet Mills called for the tobacco tax increases in her January 2025 biennial budget proposal, citing that the cigarette tax had not been increased since 2005 and had become the lowest rate in New England, which contributed to the state having the highest adult smoking rate and the second-highest youth smoking rate in the region.

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market and prohibiting characterizing flavors in cigars is likely to reduce youth smoking initiation, improve smoking cessation outcomes in adult smokers, advance health equity, and benefit public health

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