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Ellickson PL et al, High-risk behaviors associated with early smoking: results from a 5-year follow-up, J Adolesc Health, 2001 June;28(6):465-73 12

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No one knows exactly why some smokers develop COPD and others do not, although it is believed that there may be a certain genetic predisposition in this regard.2 It is notable that a large number of COPD patients smoke, even when they know that they have this condition and that it is adversely affecting the course of their disease

Finally, the projector turns off and you look out the window to see Ryan's creation for the first time