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Within one moist snuff brand from United States, Grizzly, the amount of N-nitrosonornicotine (NNN) ranged between 2.64 g/g to 11.1 g/g and while within Skoal it varied from 0.76 g/g (wet weight) to 42.6 g/g (wet weight)

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For those who manage nicotine intake carefully, inconsistent dosing may undermine efforts to reduce dependence or maintain stable usage patterns

The global harm-reduction movement is further legitimising smokeless tobacco as a viable long-term category

Usually, the bowl was made from porcelain while the shank and stem could be crafted from horn, bone or wood