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showed that impaired mitophagy due to Parkin or PINK1 deficiency leads to the accumulation of damaged mitochondria and increased inflammation via activation of the cyclic GMP-AMP synthase - stimulator of interferon genes (Sliter et al., 2018)

Editors Note: This story was produced by FairWarning (www.fairwarning.org), a nonprofit news organization based in Southern California that focuses on public health, consumer and environmental issues