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Moreover, given the infrequency of negative or zero ASP data, we do not expect in all years that alternative pricing approaches will be necessary or to affect drugs with material levels of utilization

For example, if a Part B rebatable biosimilar biological product that is currently in shortage in the calendar quarter beginning October 1, 2024, is granted a severe supply chain disruption rebate reduction request as a result of a natural disaster that occurs on October 20, 2024, CMS would apply a 75 percent reduction in the rebate amount for the duration of the calendar quarter in which the natural disaster occurred and the three subsequent calendar quarters thereafter (that is, October 1, 2024, to September 30, 2025)

CDC funds the North American Association of Central Cancer Registries (NAACCR) program, a core cancer surveillance system across the United States

The body responds to the absence of this stimulant in comparable ways regardless of delivery method

Specifically, for drugs first approved or licensed by the FDA on or before December 1, 2020, and with a first marketed date on or before December 1, 2020, the payment amount benchmark quarter would be the calendar quarter beginning July 1, 2021