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This review article highlights the need for large, carefully designed, adequately controlled, long- term follow-up clinical trials to assess the true potential of combustion-free nicotine delivery technologies for sustained smoking cessation and reducing risk of harm from smoking, particularly among smokers with chronic obstructive pulmonary disease (COPD)

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In addition, our results indicate that lower mobility and reproductive frequency serve as complementary predictors of increasing variability in species sensitivity to climate drivers

Retrieved June 7, 2026

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