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Smoking remains a leading preventable cause of premature death nationally

Cotinines half-life is 16 hours, so it reflects nicotine absorption over the preceding few days (Benowitz et al., 2002)

These findings suggest that nicotinic-acetycholine receptors may be a target for developing treatments for negative symptoms and cognitive deficits associated with schizophrenia, for which no effective treatments exist, Krystal concluded

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